Time: Sun Oct 05 07:36:56 1997
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Date: Sun, 05 Oct 1997 07:35:10 -0700
To: byronw@erols.com
From: Paul Andrew Mitchell [address in tool bar]
Subject: SLS: health, fluoride, and you  (fwd)
References: <>

Thanks, Byron!

At 10:31 AM 10/5/97 -0400, you wrote:
>Hi Paul,
>You might be interested in the book "The Master
>Cleanser"  by Stanley Burroughs.  The book is available
>from: Burroughs Books, 8905 Carter Hill Road, New
>Castle, CA, 95658, (916)-885-0624.  When I bought my
>copy, it cost $7.50 delivered.  The Burroughs method
>will clean your body of toxins.
>I've attached an article that you might also find of
>Atheroscierosis, chemistry, and nutrition:
>By J. Rinse
>Dr. Rinse is a Consulting Chemist
>	AN ATTACK OF ANGINA PECTORIS in 1951 at the age of 51 initiated an
inquiry by me into possible reasons for the Occurrence of atherosclerosis.
Starting with an hypothesis that deficiencies in my food could be causative
factors, dietary changes were explored, resulting eventually in the
complete alleviation of angina and related heart diseases.  This paper
describes the evolution of the successful dietary changes, explores details
of the hypothesis, and cites some recent work supporting important aspects
of the hypothesis.
>Following the 1951 attack of angina pectoris with attendant violent heart
aches, the attending heart specialist predicted that 1 might have another
10 years to live if all physical exercise was avoided.  I was completely
puzzled, because in my case none of the known causes was valid. I did  not
smoke, was not overweight, had no special tensions, had sufficient physical
exercise, and had no family history of the disease.  It was temporarily
assumed that I had had too much exercise cutting trees for clearance of the
building plot for my house, but this assumption did not prove valid.
>	What does a chemist do when faced with a problem? He studies literature,
makes a working hypothesis, and starts experimenting.  The literature about
aterosclerosis appeared to be very extensive; this caused me to restrict
myself to a couple of magazines, books, and articles sent by friends.  In
particular, the Journal of the American Oil Chemist Society appeared to be
very valuable because, in addition to original articles, it contained a
section of abstracts titled "Biochemistry and Nutrition." A booklet by
Coca, The Pulse Rate, also was useful.
>	My hypothesis was that there was a deficiency in my diet. The human body
is like a chemical plant, i.e., a chemical energy plant. producing various
kinds of energies, e.g., for moving and thinking, for electric energy, and
for heat. A chemical plant needs primary as well as secondary materials;
the latter being catalysts, lubricants, emulsifiers, paints, etc., which
arc used in relatively small quantities. Similarly, the human body needs
secondary materials such as minerals, metals, vitamins, and enzymes. These
are needed to run the numerous chemical reactions of metabolism, for the
production of energy, and in particular for the digestion of proteins,
fats, and carbohydrates, which arc the primary raw materials for the body.
Therefore, food must contain everything in adequate quaintly and should be
varied as much as possible.
>	A chemical plant with a shortage of secondary raw materials may continue
to work temporarily because there are reserves and substitutes but finally
disturbances will arise and the plant must stop. We have seen this during
war time in Europe. By analogy, one can expect similar disturbances in the
human body. in addition, one has to consider the yield or the efficiency of
metabolism. This yield may be too low and cause shortages by insufficient
resorption through the wall of the intestines. it should he considered that
in many cases extremely small quantities are needed, e.g., copper, cobalt,
manganese, and iron or vitamins, such as B6 and B12,. This amounts to
milligrams or less to be taken up by the average body of about 70 million
milligrams. Even when these small amounts are considered in relation to the
amount of food intake of one million milligrams per day, it will he obvious
that our food digestion process must be extremely efficient. Yields can
decrease with the age of the individual, and the consequences are
aggravated by the reduced food consumption of older persons. The body then
becomes short of some important raw materials. The use of multivitamin
pills and mixtures of minerals therefore makes sense. it is difficult to
determine which shortages prevail in a certain individual, and therefore it
is advisable to use all pertinent materials. Excesses are eliminated the
natural way.
>	The number of publications dealing with atherosclerosis has grown to such
an extent and is so controversial that a critical review has become
practically impossible. A recent publication from the N.Y. Academy of
Sciences {1} contains more than 1000 references. investigators include not
only physicians, but also biologists, biochemists, physicists, chemists,
dietitians, mechanical engineers, anthropologists, statisticians, etc., who
often are highly specialized in a limited area of the great phenomenon.
Nevertheless, it is apparent that several physical-chemical phenomena are
significant for the occurrence and course of atherosclerosis: 1) the
lubrication of the arteries by means of liquid crystals of cholesterol
derivatives to prevent damage to the arterial walls by the vigorous blood
stream; 2) the solubility of cholesterol in blood plasma and the
solubilization of cholesterol deposits; 3) the oxidation of polyunsaturated
fatty acids and formation of free radicals (which can be prevented with
antioxidants); 4) The catalytic action of enzymes; and 5) the clotting
process of blood.
>	Atherosclerosis is a metabolic disturbance by which cholesterol and
disturbance deposit in the walls of arteries, causing a more or less
hindered bloodstream. A consequence is the appearance of atherosclerotic
complications such as angina pectoris, heart infarct (coronary arteries),
cerebral thrombosis (blockage of a blood vessel to or in the brain),
claudicatio intermittent (blockage in a leg), high blood pressure (by
blocking a kidney artery), cataract, and xanthomatosis (yellow plaques
under the skin). When the process progresses further, arteriosclerosis
occurs, with hardening, and finally calcification, of the blood vessels.{2,3}
>	Cholesterol is an aromatic alcohol C,27H43OH with a melting point of
1490C. It esterifies with fatty acids and forms complexes with
phospholipids, in particular, lecithin. It is resorbed from food, -and also
formed in the liver starting with acetates. The liver produces more or less
cholesterol, depending Upon the proportion present in ingested food. The
daily requirement is only a few grams. Excess cholesterol is eliminated in
the stool. The functions of cholesterol are many, e.g., it is a component
of the cell membranes and a lubricant of the blood vessels to prevent
damage to the walls by the vigorous bloodstream. Liquid crystals of
cholesterol derivatives provide a high degree of protection to the
arteries. Cholesterol also serves as an intermediate for the biosynthesis
of bile acids, hormones, and vitamin D.
>Personal experience
>	These started in 1951 at the age of 51, with a gradually increasing
pressure or light pain in the breast after increased exercise. in the
beginning, the sensitivity disappeared immediately after the physical
activity ended, but during a hike against wind and uphill, pain began when
I did not stop, and I had a severe heart ache which made me nearly faint.
Although the pain diminished when I stopped, the light pressure in the
breast remained for several days, also during resting. A heart specialist
diagnosed angina pectoris and prescribed anticoagulant (Dicumarol) and
nitroglycerol tablets.
>	After the pressure in the breast had disappeared in a few days, I began
to work again, but avoided heavy physical activities. Also I stopped using
anticoagulant However, walking up a staircase or a hill always reminded me
that the angina was still there. because my pulse increased strongly to
become normal only after one hour.
>	The suspicion that a food deficiency caused the trouble brought me to
experiment with enzyme-rich food, such as raw herring. raw eggs. red meat,
uncooked vegetables, yogurt, etc. It is difficult to conclude whether there
was any effect.  However, the use of garlic definitely increased the
activity limit.
>Food supplements
>	In the meantime, I began to use one gram of ascorbic acid (vitamin C) per
day, because earlier I had good experiences with it for curing and
preventing colds and flu. Later a multivitamin pill was added. My breakfast
consisted of a cereal with milk and yogurt, fortified with wheatgerm,
yeast, and brown sugar (one tablespoon of each). When I read an article
about two Canadian physicians (Drs. Shute, London, Ontario) who treated
heart patients with tocopherol (vitamin E), I asked their advice and they
prescribed 200 mg vitamin E after each meal. I used these additives for
several years and, by avoiding strenuous exercise, I managed to live a more
or less normal life with only occasional warnings that the angina pectoris
was still present. I always worked until the pressure in the breast warned
me to take a rest. Also, the pulse rate was used as a control. Early 1957
and later in October of that year. I experienced attacks with heavy heart
pains, which subsided after an hour or  so. The angina pains remained after
the second attack, especially walking up stairs. At the same time, spasms
and an increase of 50 strokes in the pulse rate were observed frequently.
>	Because the possibility existed that allergy might cause the angina, I
checked this with the pulse rate and found no effect. At that time I read
about a series of experiments with rats and rabbits who got lecithin or
safflower oil, with the result that the cholesterol content in the blood
was lowered. I decided -to add a tablespoon of each to my cereal breakfast,
which contained the other additives also.
>	Results appeared in a few days because the spasms stopped and the
increased pulse rate diminished slightly but definitely. The improvement
continued until after three months all symptoms of angina pectoris, even
after exercising, had disappeared. One year later, the capacity for heavy
out-door work and running had returned. This result seemed to be too good
to be true, and in the beginning I would not believe it. But it appeared to
be a fact, because I have had no recurrence of angina or other diseases
since-now 16 years later.
>More Experiences'
>Following the advice of a Dutch physician (Dr. W. L. Ladenius), I put my
experiences in writing and gave copies to people who were interested. In
December 1960 a colleague, Dr. W., who had survived a cerebral thrombosis
and a heart infarct at the age of 53, decided to take the food supplements.
One half year later he was again working full time and lie has had no
relapse since. He is convinced that the breakfast has helped to cure him.
At the same time a 69-year old executive of Dutch industries (S.) had a
blood clot in one of his legs, used anticoagulants, and followed strict
diet without eggs or butter. Learning about my experience he cured himself
rapidly and even has started a new industry. Because he considered
safflower oil the most important supplement, he made a fat containing a
mixture of highly unsaturated oils, palm kernel fat, and nitrogen as a
substitute for butter. It is now widely used in Holland.
>After a second chemist (d.W.) also found his condition improved with (he
breakfast, we wrote a short note for the Dutch paper Chemisch Weekblad,
titled "Is Atherosclerosis Reversible?" Shortly afterwards, Chemical Week
(in U.S.A.) published two of my letters to the editor {4} about the same
subject. The results of this publicity began to spread a year later in
several letters, mostly from people we had not met. One letter written by a
man of 72 years (J.) who suffered from a series of heart attacks and angina
pectoris explained how he cured himself in three months time and was able
to take long walks again, which had been impossible during six years.
Another letter was from a Dutch mechanical engineer (R.) who, at the age of
48, had such severe angina pectoris that he had to stop working and found
no relief by drugs prescribed by several heart specialists. He did not
believe that our breakfast could help him, but after insistence of a friend
he tried it and was back to work in two months time. He can run again, and
works at times in deep-freeze storage rooms without any bad effects. A
72-year old consulting chemist (W.) from Texas had suffered from heart
attacks, read the letter in Chemical Week. and improved rapidly. He stopped
using the prescribed medicines and is again at work. A lady of 70 years
(Mrs. P.) in Manchester, Vermont had survived blockings in the neck artery
and partial paralysis. In December 1967 she started with the food
supplements, which tasted exceedingly good to her. Her health improved
rapidly and she has had no recurrences. Clinical tests showed that all
cholesterol deposits had disappeared. Numerous similar cases could be cited.
>	Besides those individual reports, I received an invitation to meet a
Dutch internist (Dr. K.) and I saw him in May 1963. He told me that he
prescribed the breakfast to numerous older patients with spectacular
results. Many of them had resumed their activities, even after having been
invalids for a long time. Six years later, Dr. K. was still enthusiastic
about the supplements.
>From other correspondents I learned that a beginning cataract disappeared
after the patient used the diet additives; this happened to two elderly
ladies. A colleague (K.) wrote me that lie regulated his wife's blood
pressure with what he called "Rinse's Morning Feed." A chemical engineer
(B.), who had worked in the sugar factories on Java, immediately accepted
our advice with the comment that he had cleaned blocked pipes in his
factory with phosphoric acid, and that therefore lecithin, being a
phosphate, might be effective for his heart condition. He indeed cured
himself and ten years later was still in good health. In 1969, a man from
Chicago (P.) wrote that he had cured himself of arthritis, and two friends
of bursitis by using the food supplements. At present several thousands of
people in Holland and U.S.A. and some in England and Belgium use the above
supplements, although most physicians ignore the method. Only some of them
advise patients not to use them.
>It is not necessary to use all of the ingredients at the same time in a
breakfast. Each person can make variations suited to his taste and need.
The most important components are lecithin and polyunsaturated oil, but the
other products may be necessary. In any case, they cannot do any harm. Some
people cannot eat yeast without stomach disturbance. In that case, more
vitamin B complex is recommended. Instead of combining the additives with
milk or yogurt, one may add them to fruit juice or to soup. One colleague
(A.) adds wheatflour, and bakes cakes that are quite tasteful. Quantities
may be varied, and less than a tablespoon can be used when all symptoms of
atherosclerosis have disappeared. It is convenient to mix all dry
components and make a supply for one month. Polyunsaturated oil can be used
by way of a soft margarine, or it can be used on salads. Besides the
previously mentioned ingredients, the use of finely ground bone meal is
recommended as a source for calcium, magnesium, phosphate, and trace
metals. Since the breakfast was developed, several papers have appeared
confirming various aspects of the working hypothesis. Some important
corroboration comes from studies of cholesterol.
>Cholesterol content
>	Although statistically the chance for atherosclerosis is higher if the
cholesterol content of blood is high, many persons are healthy with a high
cholesterol content. This has been discussed by van Buchem in his
publications.{5-7} Therefore it is doubtful whether the efforts to lower
cholesterol content by all means are justified. Such efforts include
avoidance of food containing cholesterol such as eggs and butter, or using
drugs that affect the production of cholesterol in the liver. it has been
demonstrated that the liver produces more cholesterol if food contains
less. Reducing its production by the liver by means of drugs can be
dangerous and has caused serious side effects, such as cataracts and the
loss of hair It seems that one cannot change cholesterol production in the
body without penalty. On the other hand, if lecithin is added to the diet,
the unwanted deposits of cholesterol derivatives do not form, because the
lecithin-cholesterol compound is soluble. Both materials occur in eggs, and
therefore an atherosclerotic patient should not deprive him-self of eating
eggs. We have seen that polyunsaturated oil also should be present. Any
excess of cholesterol in the bloodstream is removed from the body through
the intestines.{8}
>	The complex of cholesterol with lecithin occurs in the molecular ratio of
1:1{9.10} and is found in several parts of the body. Lecithin is a
glyceride with two fatty acid groups (mostly linoleate) and a
phosphate-choline group, and therefore it is actually a combination of two
vitamins and a mineral. Choline is a member of the vitamin B complex group.
The transition point of the cholesterol-lecithin complex from the solid to
the liquid crystalline state varies with the degree of saturation of the
fatty acids, being 700C with stearate and 00C with linoleate.{11}  The
transition points arc lower with shorter chain fatty acids, such as those
with ten carbon atoms (as present in butter and Coconut fat). These are
called medium chain triglycerides (MCT).{12.13}
>	It is obvious to relate the incidence of atherosclerosis to the melting
point of the cholesterol derivatives. Too little lecithin and too little
linoleate cause the deposits to be solid at body temperature. Small {11}
has investigated the phase equilibria in the quaternary system
cholesterol-lecithin-bile salts-water. He reports that cholesterol is
soluble in the homogeneous phases only if adequate lecithin is present.
This lecithin should contain a sufficient quantity of linoleate groups in
order to cause the complex with cholesterol to melt at or below blood
temperature. Saundcrs and Wells{14} have reported that this type of
lecithin also is capable of dissolving bile stones, which are known to
contain a large quantity of cholesterol.
>	Recently Zilversmit and Adams'{15} discussed the process by which
polyunsaturated lecithin dissolves cholesterol deposits in the arterial
wall. Apparently lecithin supplies the linoleic acid, which esterifies
cholesterol. This ester is more easily removed from the wall tissues than
the saturated esters.
>	Assuming that the main problem of atherosclerosis is to keep cholesterol
in solution and to dissolve its deposits in the arterial walls, then it is
apparent that the diet should contain lecithin in sufficient amounts.
Lecithin occurs in nuts, seeds, eggs, and soybeans, and is produced in
commercial quantities from soybean oil. The linoleate content depends upon
the climate and the geographical source. The technical product contains
other phospholipids {16} Lecithin and other lipids are hydrolyzed by
metabolism into, smaller molecules,{17} which pass through the intestinal
wall and reconvert into lecithin in the liver. Because the great majority
of fatty acids in human food are of the saturated type, chances are that
the lecithin produced in the liver will contain these fatty acids in larger
quantities. Therefore, the addition of some polyunsaturated oil
(linoleates) simultaneously with lecithin is desirable to obtain low
melting derivatives. The daily requirements of lecithin and polyunsaturated
fatty acids are of the same order as those for cholesterol, being a few
grams per day. The molecular weight of lecithin being about twice that of
cholesterol, one needs 4 to 6 g of lecithin and an equal amount of
linoleate per day. If, however, a condition of more or less advanced
atherosclerosis exists, the amounts of lecithin and oil should be
increased. Morrison {18} prescribed the previously mentioned amount of
lecithin for his patients three times per day. However, some patients could
not tolerate this much, and therefore lesser amounts may be indicated.
Linoleate is also an intermediate for the production of the prostaglandin
>	The consumption of polyunsaturated oils by themselves (without lecithin)
would not be effective, as one can conclude from the preceding
consideration. Only in the presence of sufficient lecithin can the
polyunsaturated fatty acid help in dissolving cholesterol. in countries
with high fish consumption, such as Norway, the addition of polyunsaturated
oils alone did not have any effect. it is lecithin that they need It is
understandable that van Buchem {6} after an extensive investigation reaches
the following conclusion: "The advice to recommend the Consumption of
polyunsaturated oils by the whole population with the exclusion of
saturated fats, is insufficiently founded."
>	The same medical scientist, together with the Gaubius Institute in
Leiden, Holland (Pries et al.){7} has analyzed the blood of 48 men between
40 and 60 years of age, half of whom had atherosclerotic complications and
the other half had not. Men having a lecithin content of 36 percent or
higher in the blood fats showed no atherosclerosis, whereas those with 34
percent or lower all had the disease. The conclusion drawn: "One should,
based on the results of our investigation, increase the phospholipid
percentage of the blood and the lecithin percentage of the lipids."
>	Polyunsaturated oils are oxidized easily, especially in the oxygen-rich
arterial blood medium. Natural products contain antioxidants, in
particular, tocopherol (vitamin E), and lecithin. When oils are refined,
these antioxidants are removed with the so-called foots. Linseed oil, for
example, does not dry (oxidize) before refining. Drying is required for
paints, but the oil should not oxidize for human consumption in order to
avoid the formation of free radicals that may cross-link tissues in the
body, causing rigidity and loss of flexibility in arteries and muscles.
Such cross-linking within the arterial walls would increase the probability
that internal bleeding could occur. Therefore, it makes sense to add to the
diet some vitamin E{19 to 21} and also some ascorbic acid (vitamin C),
which is a water-soluble antioxidant. Both vitamins assist in dissolving
blood cholesterol deposits {22,23}. Drs. Shute{24} in Canada recommended
consumption of large quantities of tocopherol for preventing heart disease.
Similar claims are made for ascorbic acid {22,23} in large quantities. If
used with lecithin and linoleate, the needed quantities by our experience
are smaller, i.e.,, 100-200 mg of vitamin E and 500-1000 mg of vitamin C
Vitamin E also regulates the clotting time of blood and dilates the blood
>	A fourth antioxidant is sulfur and its derivatives. Their activity is
known but not yet fully explained. They prevail in garlic and onions, and I
experienced the beneficial influence on angina pectoris. In France the
farmers feed their horses garlic and onions to cure atherosclerotic
obstructions  in the legs. Literature references indicate the usefulness of
sulfur with arthritis and other diseases.
>	A very old, but still used medicine is Haarlemmer Oil, which is prepared
by heating a mixture of linseed oil, sulfur, and turpentine. Although
pharmacists and physicians denounce its value, it may be  that a product
such as this can have some merit after all.
>Other trace materials
>	The literature contains many publications dealing with vitamins and with
minerals{25} in relation to atherosclerosis. Among these are pyridoxine
(vitamin B.) and nicotinic acid, belonging to the B complex group. The
metals iron and calcium have been investigated extensively. Data about
magnesium and several trace metals such a; manganese, cobalt, zinc,
chromium, potassium, copper, and vanadium {26} are available. Other needed
minerals include iodine, phosphorus, sulfur, and selenium. The latter are
noted for their antioxidant activity.
>	Drinking water containing calcium has been found to lessen mortality
induced by atherosclerosis, as was determined by comparing the mortality
rate for Glasgow, which had soft water, with the mortality rate for London
with its hard, calcium-containing water. The rate in London was
considerably lower. Schroeder,{27} an authority on trace minerals, found
that chromium prevails in brown sugar, and that rats fed on a diet with
high sugar content have less cholesterol in their blood if the sugar is
unrefined, or if a trace of chromium is added to refined sugar.
>	Vitamins and minerals are needed for the formation of many enzymes.
Enzymes act as catalysts in metabolic processes. Some enzymes regulate the
digestion of food by splitting it into smaller assimilable molecules. Other
enzymes function in metabolic synthesis. Several enzymes play a part in
adenosine triphosphate functions such as muscular contraction, carbohydrate
metabolism, and body temperature control. Many enzymes are organic metal
derivatives with very specific activities. If the metal is lacking in the
diet, the body's supply gradually becomes exhausted, and some of the
metabolic functions are disturbed, resulting in disease. It is possible
that not all disturbances in hormone functions can be cured with vitamins
and minerals. In those cases, special pharmaceuticals may be needed.
>	As we have seen, clotting of the blood can aggravate atherosclerosis by
the closing of narrowed arteries. Excessive speed of blood in such blood
vessels damages the blood and causes clotting. This may be prevented with
an anticoagulant, usually derivatives of cumarol, also used to poison the
arrows of South American Indians. Clotting time is regulated with the
quantity of cumarol derivative, larger quantities prevent clotting
completely, which is undesirable in case of an internal wound or after an
accident. People have died by hemorrhages because of too large quantities
of cumarol. It seems that the use of an anticoagulant is justified when the
patient has complete bed rest, i.e., during the few weeks following an
infarct or other blocking. However, as soon as activity is resumed, the use
of anticoagulant is doubtful and even dangerous for people with hardened or
weakened arteries.{28} Instead of cumarol derivatives, it might be better
to use vitamins (E and K), which regulate the Clotting time in a more
natural and less dangerous way. Also, it should be kept in mind that
several of the drugs administered to patients increase the activity of the
>Natural! or synthetic supplements
>	Many people reject the consumption of synthetic materials, and even
advocate the use of manure instead of chemical fertilizers (organic
gardening) because they are afraid that mass-produced food does not contain
all essential vitamins and minerals. Instead of rejecting synthetics and
chemicals, they could more easily and economically us". the previously
mentioned food supplements. Probably the combination of natural and
synthetic products is the best way to obtain food without deficiencies.
There should be no doubt that chemicals such as ascorbic acid (vitamin C),
thiamin (vitamin B1), riboflavin (vitamin B,), and cyanocobalamin (vitamin
B,1) are very valuable additives, which have helped numerous sick people.
>Is atherosclerosis reversible?
>	This question, which we discussed in 1961 in Chemisch Weekblad and in
Chemical Week. now can be answered affirmatively. At least less severely
stricken and younger patients appear to have been cured completely without
restriction of normal physical activity. This means that the cholesterol
deposits in their blood vessels have been solubilized, and the narrowing
has disappeared. The same has happened with older patients (65-80 years),
and they felt relief and resumed activity. However, if their arteries have
already lost flexibility or contain weak spots and calcium deposits
(arteriosclerosis) (hen they should be cautious not to strain them-selves
so as to prevent internal hemorrhages. Several cases have been reported.
After full recovery from atherosclerosis, physical activity is desirable to
train heart, lungs, and other organs, and to help prevent recurrence of
>	The recommended and proven natural products to be used are soybean
lecithin, wheat germ, brewers yeast, and bone meal, available as powders or
grains or flakes, which can be mixed and stored indefinitely, provided
light is excluded. A practical ratio is 4:4:4:1, and daily requirement is
only 15-25 g (two tablespoons) of the mixture. It may be consumed with milk
or with fruit juice or with soup. A polyunsaturated oil (five grams) should
be added, and finally these natural additives should be supplemented with
synthetic (or natural) vitamins C and E and a multivitamin-mineral tablet.
If sugar is desired, the dark brown quality or molasses syrup or honey
should he used.
>	Although I have concentrated on finding a cure for atherosclerosis, I
have learned that the food supplements also have been helpful in several
other diseases, such as colds, flu, infections, arthritis, bursitis, and
backache. It is probable that they also prevent these troubles, based on my
experience. Several correspondents have written to me about such effects.
>Contributory !actors
>	Our working hypothesis is that food deficiencies are the main cause for
atherosclerosis, and therefore all other known influences, such as tension,
smoking, obesity, and maybe also heredity, are only contributory. Lack of
exercise makes it difficult to detect atherosclerosis in an early stage.
>	Smoking deactivates vitamins. The abnormal way of life of people who push
themselves too much affects either the nervous system or the blood vessels,
or frequently both. These people can protect their arteries by using food
supplements. Their bodies use more vitamins, and therefore must receive
supplements. It should be instructive to investigate whether people who are
atherosclerotic because of heredity (familial hypercholesterolemia) can be
cured by the food supplements. We know of one case of two brothers whose
parents died because of atherosclerosis. One brother used the supplements
and remained healthy. The other was stricken but has now recovered after
using the supplements.
>	A recent study {29} of 575 pairs of Irish brothers sheds some light on
environmental and hereditary factors. From each pair, one had emigrated to
the Boston area and the other brother remained in Ireland. A thorough
comparison was made by teams of U.S. and Irish physicians and nutritionists
regarding the heart condition and way of life of each of the men. It
appeared that the remaining Irish men had more healthy hearts in all
respects than their emigrated brothers, notwithstanding that the diet of
the Irish men was much heavier in calories, saturated fats, butler, bacon,
and potatoes than the regular U.S. diet. It was noticed that the Irish men
were drinking tea and beer, while their U.S. brothers drank coffee and
distilled liquor. No significant differences were found with smoking habits
or with stress, two factors often said to cause atherosclerosis. On the
other hand, the Irish men had much. more physical exercise than their U.S.
brothers. The reporting scientists consider this of greatest importance. A
second difference is that the Irish diet contained considerably more
calcium and magnesium, and it is said that the latter metal is favorable
for calcium metabolism. The same is claimed for the fluoride content of the
tea the Irish men were drinking. No mention is made of differences in
drinking water.
>	This study does not confirm that heredity, smoking, and stress are the
principal causes of heart disease, as is so often assumed by physicians.
However, these factors probably contribute to the disease after it has
started through deficiencies in the diet. Exercise causes greater food
consumption, and therefore deficiencies of vitamins and minerals may be
diminished or eliminated. The Irish investigation is not in agreement with
the assumption that cholesterol-containing food should be avoided.
Apparently such food is not as bad as frequently assumed. Therefore,
butter, milk, and eggs do not need to be avoided.{30}
>Let us now consider why deficiencies occur:
>1)	Refining of foodstuffs: Vegetable oils are filtered, because a turbid
oil is unattractive and difficult to sell. This process removes lecithin
and tocopherol. Cereals are ground and sifted to remove hulls (which
contain vitamins) and debris. Many people prefer white bread over brown
bread and do not receive the needed vitamins; this is only partially
corrected with the addition of thiamin to bread flour. Refining sugar
removes all of the mineral components present in beet or reed juices.
>2)	Decreased consumption because of reduced physical exercise or because
of age.
>3)	Malabsorption, giving rise to metabolic dysfunction: Faulty digestion
may be the cause of the deficiency. It is likely that Malabsorption grows
greater with age. There may be a hereditary factor.
>	Refining is unavoidable in modern society, but one can choose foods like
nuts, seeds, milk and other dairy products, honey, and vegetables that have
not been refined. Eating more raw food supplies more vitamins. Organic
gardening or (so-called biodynamical growing) probably supplies more
vitamins and minerals, because the harvests without inorganic fertilizers
are much smaller, and the concentrations of some minor components
(minerals) accordingly may be higher. For most people this method is
cumbersome, and it would cause famine if generally adopted.
>	A more efficient and easier-to-follow method for supplementing the diet
is needed. Because our knowledge about the required vitamins and minerals.
is not yet complete, a combination of natural products known to be rich in
vitamins or minerals should be made and fortified with concentrated
synthetic or natural vitamins and minerals. This supplement should be taken
in addition to regular diets, since it can be consumed in endless varieties.
>The personal experiences of a considerable number of chemists, physicians,
and other individuals whom I know suggest the following preliminary
conclusions, which are offered here for consideration and continued
>1) 	Atherosclerosis is a deficiency disease, which can be counteracted
successfully by the use of food supplements, in particular of lecithin and
unsaturated oils.
>2) 	Atherosclerosis is a complicated chemical problem, which should be
studied along basic
>	chemical lines, e.g., The Law of Mass Action and the Phase Rule, and by
application of existing knowledge about antioxidants, free radicals, liquid
crystals, etc.
>3) 	Atherosclerosis can be accelerated by contributory factors such as
smoking, mental stress, heredity, obesity, and lack of physical exercise.
>4) 	It probably is unnecessary. and even undesirable, to replace all fats
by unsaturated oils.
>5) 	Diet additives act favorably on many other diseases in addition to
>	Finally, a word of thanks to all who have informed me about their
experiences with the diet, and to those who have sent me literature about
atherosclerosis have discussed this with me: in particular, to Dr. C. I.
Kruisheer. L. P. Mayrand, and Dr. Cl. W. Sondern and to the physicians Dr.
F. S. P. van Buchem, Dr. A. K. J. Koumans, and Dr. W. L. Ladenius.
>Food supplement for prevention and cure of atherosclerosis
>The following combination of natural and synthetic vitamins and minerals
has proved to be beneficial for the cure and prevention of atherosclerotic
complications, such as high blood pressure. angina pectoris, cataract.
obstructions in the arteries of neck. legs. arms, and kidneys.
Consequently, heart infarcts and cerebral thrombosis become avoidable.
>A mixture is made of one tablespoon each of soybean lecithin, debittered
yeast. and raw wheatgerm and one teaspoon of bone meal (ash). (It is
recommended to prepare a larger quantity for storage.)
>Mix in a bowl:
>Two tablespoons of the above mixture.
>one tablespoon of dark brown sugar.
>one tablespoon of safflower oil or other linoleate oil. e.g.. soybean oil.
>Add milk to dissolve sugar and yeast.
>Add yogurt to increase consistency.
>Add cold cereal for calories as needed or mix with hot cereal such as
oatmeal or porridge. Raisins and other fruits can be added as desired.
>For severe cases of atherosclerosis the quantity of lecithin should be
>Finally. it is recommended to take daily: 500 mg(1/2 g) of ascorbic acid
(vitamin C) and 100 l.U. vitamin E and one muItivitamin-mineraI tablet.
>Any other normal food may be used. including eggs and butter, but
high-melting fats (regular margarine) must be avoided. Soft
(linoleate-containing) margarines are helpful. but butler is preferred.
because it contains medium-chain-triglycerides (MCT fat).
>The above given supplements act as follows:
>a.	Linoleate-containing lecithin, after being reconstituted in the liver,
combines with cholesterol and forms a blood-soluble lipid, removable from
the body by excretion. In this way the arteries become widened again.
>b.	Antioxidants, vitamins C and E. prevent oxidation of linoleate in the
bloodstream and therefore cross-linking of tissues and loss of flexibility.
Also colds and other virus diseases may be prevented by these vitamins.
>c.		Supply the metabolism with ingredients for the production of enzymes,
the catalyst for numerous reactions In the body. They comprise many
vitamins, metals, and trace metals, also iodine and suflur. 
>Atherosclerosis appears to be caused by food deficiencies and aggravated
by smoking, obesity, heredity, lack of exercise, and mental tension.
>  I.		"Atherosclerosis. recent advances" Ann. N.Y. Acad. Sci. 149. 585-1068
>		(Nov. 1968).
>  2.		ADLERSBERG, D. J.  Amer. Med. Assoc. 162 ((2/23/95, PAGE #'s
obscured on original photocopy)) (1956).
>  3.		SCHROEDER. H. A.. "Review,": Med. Sci. (Jan. 25, 1960).
>  4.		RINSE, J., Letter to editor. Chem. Week  (March 26. 1966),(Sept. 16.
>		(Jan. 13,1971)
>  5.		VAN BUCHEM, F. S. P., "Atherosclerosis and nutrition," Nutr. Dieta
4, 122-147 	(1962).
>  6.		VAN BUCHEM. F. S. P., "Pathogenese en preventie van atheroscIerose en
>		atherosclerotische complicatie's"  Ned. Tydschr, v. Gcneeskunde 115,.
>		1311 (1971).
>  7.		Pries C., VAN BUCHEM, F. S. P.,  et al.,  "Bloedlipiden en 
>			atherosclerotische complicatie's." Ned. Tydschr. v . Geneeskunde III,
1594 				(1967)
>  8.		PASSWATER, R. A., "Dietary cholesterol: is it related to serum
>			and heart disease?" Amer. Lab. 4 (9). 23-35 (1972).
>  9.		VANDENHEUVEL, F. A., "Study of biological structure at the molecular
>		J. Amer. Oil Chem. Soc. 40. 464 (1963)
>10.	KRICKAG, G., "Therapie der atherosklerose mit olen und phosphatiden."
>		Monatschrifte 16 (2) (1962)
>11.		SMALL, D. M., "A classification of biologic lipids based upon their
interaction in
>		aqficous systems." J. Amer. Oil Chem. Soc. 45 (3). 108 (1968).
>12.		HOLD, P. R., Medium Chain Triglycerides (Year Book Medical Publishers
>		1971) 	DM Series.
>13.		KING, C., ((2/23/95, These letters obscured on photocopy.)) "Biological 
>		medical aspects of fats." J. Amer. Oil Chem. Soc. 47, 418 A-443A (1970)
>14.		SAUNDERS, D. R., "The cholesterol solubilizing capacity of lecithin
in aqueous 
>		solutions of bile salts." Biochim. Biophys.Acta 176, 828 (1969)
>15.		ZILVERSMIT, D. B. and ADAMS, C. W., Atherosclerosis, edited by R. J.
>		(Springer Verlag, New York, 1970. pp. 28, 35.
>16.		STEINKOFF, G., Ullman's Encyklopadic der Technischen Chemie (Urban and
>		Schwartzenberg, Berlin 1969), 3rd ed. vol. 11, pp. 546-550
>17.		MACLEAN, H., and MACLEAN, L. S., Lecithin (Longmans Green, London, 1927)
>18.		MORRRISON,  L. M., "Serum cholesterol reduction with lecithin."
Geriatrics 13, 12
>		(1958)
>19.		BAILEY, H., Vitamin E  (ARC Books, New York).
>20.		"Vitamin E: what's behind all those claims for it?"  Consumer Reports
38 (1), 60-66 
>		(1973).
>21.		Vitamin E and its role in cellular metabolism."  Ann. N.Y. Acad. Sci.
>		(Dec. 1972).
>22.		SPITTLE, C. R., The Lancet 1280, 1281 (Dec. 11, 1971) 
>23.		SOKOLOFF, B., "Aging, atherosclerosis and ascorbic acid metabolism."
J. Amer. Ger.Soc. 14, 1239-1260 (1966).
>24.		SHUTE, W. E. TAUB. H. J., Vitamin E. for ailing and Healthy Hearts
(Pyramid Publications, New York, 1969.)
>25.		SCHROLDER, H. A., "Trace metals." Today's Health (March 1966)(
>26.	SCHWARTZ, K. and MILNE, D. B., "Vanadium." Science (Oct. 22, 1971).
>27.	SCHOLDER, H. A., "Sugar." J. Nutri. 97.237 (1969).
>28.	SANDLRS, H. S., " Heart disease." Chem. Eng. News (March 8 and 22, 1965).
>29.	BROWN, J., et al., "Nutritional and epidemiologic factors related to
heart disease." 
>	World Rev. Nutri. Diet. 12, 1-42 (1970)
>30.	"Symposium on atherosclerosis and nutrition." Neth. Milk Dairy J. 12,
>	(1958).

Paul Andrew Mitchell, Sui Juris      : Counselor at Law, federal witness 01
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